WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:nervous system development       ID:GO:0007399
C=1724; O=19; E=4.24; R=4.48; rawP=2.43e-09; adjP=1.14e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
2  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
3  ENSG00000125851 NA PCSK2 proprotein convertase subtilisin/kexin type 2 5126 ENSG00000125851
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
7  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
9  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
10  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
11  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
12  ENSG00000188487 NA INSC inscuteable homolog (Drosophila) 387755 ENSG00000188487
13  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
14  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
15  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
16  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
17  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
18  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
19  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:biological process       Name:neurogenesis       ID:GO:0022008
C=1140; O=15; E=2.81; R=5.35; rawP=2.53e-08; adjP=5.92e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
6  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
7  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
8  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
9  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
10  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
11  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
12  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
13  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
14  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
15  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:biological process       Name:generation of neurons       ID:GO:0048699
C=1073; O=14; E=2.64; R=5.30; rawP=9.84e-08; adjP=1.54e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
6  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
7  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
8  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
9  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
10  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
11  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
12  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
13  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
14  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:biological process       Name:cellular developmental process       ID:GO:0048869
C=2829; O=17; E=6.96; R=2.44; rawP=0.0001; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
2  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
3  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
4  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
5  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
6  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
7  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
8  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
9  ENSG00000188487 NA INSC inscuteable homolog (Drosophila) 387755 ENSG00000188487
10  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
11  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
12  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
13  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
14  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
15  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
16  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
17  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:biological process       Name:glial cell differentiation       ID:GO:0010001
C=146; O=5; E=0.36; R=13.92; rawP=2.72e-05; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
3  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
4  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
5  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449


Database:biological process       Name:lens induction in camera-type eye       ID:GO:0060235
C=7; O=2; E=0.02; R=116.11; rawP=0.0001; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000181449 NA SOX2 SRY (sex determining region Y)-box 2 6657 ENSG00000181449
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:biological process       Name:neuron development       ID:GO:0048666
C=798; O=9; E=1.96; R=4.58; rawP=0.0001; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000092758 NA COL9A3 collagen, type IX, alpha 3 1299 ENSG00000092758
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
5  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203
6  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
7  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
9  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:biological process       Name:regulation of synaptic transmission, glutamatergic       ID:GO:0051966
C=31; O=3; E=0.08; R=39.33; rawP=5.87e-05; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
2  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
3  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:biological process       Name:cell adhesion       ID:GO:0007155
C=954; O=10; E=2.35; R=4.26; rawP=7.08e-05; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000215018 NA COL28A1 collagen, type XXVIII, alpha 1 340267 ENSG00000215018
4  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
7  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
8  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
9  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
10  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:biological process       Name:transmission of nerve impulse       ID:GO:0019226
C=735; O=9; E=1.81; R=4.98; rawP=5.37e-05; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000108381 NA ASPA aspartoacylase 443 ENSG00000108381
3  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
4  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
5  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
6  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
7  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
8  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
9  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:molecular function       Name:RNA polymerase II distal enhancer sequence-specific DNA binding       ID:GO:0000980
C=16; O=2; E=0.03; R=57.89; rawP=0.0005; adjP=0.0344
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:RNA polymerase II core promoter proximal region sequence-specific DNA binding       ID:GO:0000978
C=24; O=2; E=0.05; R=38.60; rawP=0.0012; adjP=0.0344
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:enhancer sequence-specific DNA binding       ID:GO:0001158
C=25; O=2; E=0.05; R=37.05; rawP=0.0013; adjP=0.0344
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:enhancer binding       ID:GO:0035326
C=28; O=2; E=0.06; R=33.08; rawP=0.0016; adjP=0.0344
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:core promoter proximal region DNA binding       ID:GO:0001159
C=36; O=2; E=0.08; R=25.73; rawP=0.0027; adjP=0.0387
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:core promoter proximal region sequence-specific DNA binding       ID:GO:0000987
C=35; O=2; E=0.08; R=26.47; rawP=0.0026; adjP=0.0387
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:molecular function       Name:channel activity       ID:GO:0015267
C=420; O=4; E=0.91; R=4.41; rawP=0.0123; adjP=0.0713
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
2  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
3  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
4  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:molecular function       Name:substrate-specific channel activity       ID:GO:0022838
C=402; O=4; E=0.87; R=4.61; rawP=0.0106; adjP=0.0713
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
2  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
3  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
4  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:molecular function       Name:cell adhesion molecule binding       ID:GO:0050839
C=56; O=2; E=0.12; R=16.54; rawP=0.0065; adjP=0.0713
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
2  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915


Database:molecular function       Name:RNA polymerase II regulatory region sequence-specific DNA binding       ID:GO:0000977
C=73; O=2; E=0.16; R=12.69; rawP=0.0108; adjP=0.0713
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
2  ENSG00000137203 NA TFAP2A transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) 7020 ENSG00000137203


Database:cellular component       Name:intrinsic to membrane       ID:GO:0031224
C=5437; O=29; E=13.71; R=2.12; rawP=1.79e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
5  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
6  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
7  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
8  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
9  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
10  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
11  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
12  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
13  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
14  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
15  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
16  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
17  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
18  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
19  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
20  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
21  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
22  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
23  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
24  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
25  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
26  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
27  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
28  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
29  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:integral to membrane       ID:GO:0016021
C=5321; O=28; E=13.42; R=2.09; rawP=4.80e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
5  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
6  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
7  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
8  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
9  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
10  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
11  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
12  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
13  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
14  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
15  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
16  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
17  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
18  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
19  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
20  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
21  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
22  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
23  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
24  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
25  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
26  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
27  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
28  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:membrane part       ID:GO:0044425
C=6154; O=30; E=15.52; R=1.93; rawP=7.22e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
4  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
5  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
6  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
7  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
8  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
9  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
10  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
11  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
12  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
13  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
14  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
15  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
16  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
17  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
18  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
19  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
20  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
21  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
22  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
23  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
24  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
25  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
26  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
27  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
28  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
29  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
30  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:integral to plasma membrane       ID:GO:0005887
C=1220; O=12; E=3.08; R=3.90; rawP=3.26e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
5  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
8  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
9  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
10  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
11  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
12  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772


Database:cellular component       Name:plasma membrane part       ID:GO:0044459
C=1918; O=15; E=4.84; R=3.10; rawP=3.88e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
5  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
6  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
7  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
8  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
9  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
10  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
11  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
12  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
13  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
14  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
15  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910


Database:cellular component       Name:intrinsic to plasma membrane       ID:GO:0031226
C=1264; O=12; E=3.19; R=3.77; rawP=4.62e-05; adjP=0.0006
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
2  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
3  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
4  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
5  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
8  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
9  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
10  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
11  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
12  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772


Database:cellular component       Name:axon       ID:GO:0030424
C=286; O=6; E=0.72; R=8.32; rawP=7.64e-05; adjP=0.0009
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
2  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
3  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
4  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
5  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
6  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:cellular component       Name:membrane       ID:GO:0016020
C=7811; O=32; E=19.70; R=1.62; rawP=0.0001; adjP=0.0010
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000112077 NA RHAG Rh-associated glycoprotein 6005 ENSG00000112077
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000125851 NA PCSK2 proprotein convertase subtilisin/kexin type 2 5126 ENSG00000125851
4  ENSG00000185985 NA SLITRK2 SLIT and NTRK-like family, member 2 84631 ENSG00000185985
5  ENSG00000046653 NA GPM6B glycoprotein M6B 2824 ENSG00000046653
6  ENSG00000089356 NA FXYD3 FXYD domain containing ion transport regulator 3 5349 ENSG00000089356
7  ENSG00000146013 NA GFRA3 GDNF family receptor alpha 3 2676 ENSG00000146013
8  ENSG00000125355 NA FAM70A family with sequence similarity 70, member A 55026 ENSG00000125355
9  ENSG00000100146 NA SOX10 SRY (sex determining region Y)-box 10 6663 ENSG00000100146
10  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
11  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
12  ENSG00000180772 NA AGTR2 angiotensin II receptor, type 2 186 ENSG00000180772
13  ENSG00000117069 NA ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 81849 ENSG00000117069
14  ENSG00000147255 NA IGSF1 immunoglobulin superfamily, member 1 3547 ENSG00000147255
15  ENSG00000021645 NA NRXN3 neurexin 3 9369 ENSG00000021645
16  ENSG00000103429 NA BFAR bifunctional apoptosis regulator 51283 ENSG00000103429
17  ENSG00000110900 NA TSPAN11 tetraspanin 11 441631 ENSG00000110900
18  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
19  ENSG00000158887 NA MPZ myelin protein zero 4359 ENSG00000158887
20  ENSG00000144847 NA IGSF11 immunoglobulin superfamily, member 11 152404 ENSG00000144847
21  ENSG00000184564 NA SLITRK6 SLIT and NTRK-like family, member 6 84189 ENSG00000184564
22  ENSG00000164626 NA KCNK5 potassium channel, subfamily K, member 5 8645 ENSG00000164626
23  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873
24  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
25  ENSG00000123560 NA PLP1 proteolipid protein 1 5354 ENSG00000123560
26  ENSG00000186684 NA CYP27C1 cytochrome P450, family 27, subfamily C, polypeptide 1 339761 ENSG00000186684
27  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
28  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
29  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
30  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
31  ENSG00000206579 NA XKR4 XK, Kell blood group complex subunit-related family, member 4 114786 ENSG00000206579
32  ENSG00000182272 NA B4GALNT4 beta-1,4-N-acetyl-galactosaminyl transferase 4 338707 ENSG00000182272


Database:cellular component       Name:synapse       ID:GO:0045202
C=489; O=7; E=1.23; R=5.68; rawP=0.0002; adjP=0.0018
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
2  ENSG00000175161 NA CADM2 cell adhesion molecule 2 253559 ENSG00000175161
3  ENSG00000065361 NA ERBB3 v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) 2065 ENSG00000065361
4  ENSG00000196338 NA NLGN3 neuroligin 3 54413 ENSG00000196338
5  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
6  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
7  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873


Database:cellular component       Name:cell projection part       ID:GO:0044463
C=639; O=7; E=1.61; R=4.34; rawP=0.0010; adjP=0.0081
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000237515 NA SHISA9 shisa homolog 9 (Xenopus laevis) 729993 ENSG00000237515
2  ENSG00000167614 NA TTYH1 tweety homolog 1 (Drosophila) 57348 ENSG00000167614
3  ENSG00000179915 NA NRXN1 neurexin 1 9378 ENSG00000179915
4  ENSG00000162951 NA LRRTM1 leucine rich repeat transmembrane neuronal 1 347730 ENSG00000162951
5  ENSG00000149571 NA KIRREL3 kin of IRRE like 3 (Drosophila) 84623 ENSG00000149571
6  ENSG00000198910 NA L1CAM L1 cell adhesion molecule 3897 ENSG00000198910
7  ENSG00000163873 NA GRIK3 glutamate receptor, ionotropic, kainate 3 2899 ENSG00000163873




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).